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Analytical Toxicology


The course covers the fundamental aspects of analytical toxicology and its applications, including the entire range of qualitative and quantitative chemical and physical techniques used in sample preparation, separation, assay calibration, detection and identification, and quantification for toxicological research and testing. Various types of modern analytical instrumentation (spectrophotometry, chromatography, electrophoresis, mass spectrometry) and sample preparation techniques (solid, liquid and volatile compounds) will be introduced in this course. The course will also discuss the data interpretation derived from the analytical instrument. The course will introduce the method development and validation procedure, which are relevant to the chemical industries and related regulatory agencies. The module will be delivered as blended learning that involves theoretical components delivered through an online interface and practical sessions delivered face-to-face as a separate module (elective module). Additional costs may be applied for the elective module. Candidates may opt not to enrol in the hands-on session by taking only online classes, in which the certificate will be issued according to the enrolment plan.


The objectives of the module are to:

1. introduce the fundamental analytical toxicology and its applications
2. provide the essential knowledge and skills on an analytical instrument for toxicology analyses

Learning Outcome

At the end of the course, upon completing the module, the participant will be able to:

1. demonstrate knowledge of the principles of analytical toxicology
2. apply the knowledge and skills of analytical toxicology to conduct independent and innovative research
3. demonstrate high ethical and professional standards and responsible conduct in research
4. synthesise the knowledge and skills of analytical toxicology to succeed as a professional in diverse toxicology careers

The topics covered in this module:
- Introduction to analytical toxicology
- Instrumental analysis
- Sample preparation
- Method development and validation
- Special topic on analytical toxicology
- Practical 


MYR 350per module

Non USM (Local)

MYR 450per module

Non USM (International)

USD 200per module

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Expertise : Analytical chemistry; green separation; nanomaterials; chromatography and electrophoresis

ChM Dr. Noorfatimah Yahaya was trained as an analytical chemist in the fields of separation chemistry, including chromatography and electrophoresis, as well as the development of green sample preparation procedures employing nanomaterial sorbents. Currently, she is a senior lecturer in the Department of Toxicology at the Advanced Medical and Dental Institute of Universiti Sains Malaysia. She has published more than ninety peer-reviewed scientific articles in journals such as Food Chemistry, Talanta, and the Journal of Separation Science. Over the years, she and her students have made substantial contributions to analytical and bioanalytical method development, as well as the application of mass spectrometry in conjunction with separation technologies.


PENSYARAH UNIVERSITI DS51 Degree of Doctor of Philosophy (Analytical Chemistry), Universiti Malaya (2015) Degree of Mater of Science (Analytical Chemistry and Instrumental Analysis), Universiti Malaya (2011) Degree of Bachelor of Science (Analytical and Environmental Chemistry), Universiti Malaysia Terengganu (2009)
Expertise : Analytical Chemistry

Dr. Nur Nadhirah Mohamad Zain is a senior lecturer at the Department of Toxicology, USM since 2015. She obtained her Doctor of Philosophy, PhD, in the Analytical Chemistry with specialization in separation science from University of Malaya in 2015. She has been actively involved in research includes the development of new green magnetic/non-magnetic materials for the application of separation techniques in separation and adsorption. She delivers her skills and expertise through scientific publications, student supervisions, and service consultation. She also involves in reputable publisher as a reviewer such as Elsevier journal. She has acquired professional training in Safety in the Use of Chemicals (NIOSH), ICOP CLASS 2014 Implementation for Chemical Classifier (MIHA), MS ISO/IEC 17025:2017 (MMIC) and Procedure of Method Validation and Verification (MMIC). Currently, her research interests are focusing on development of green materials based deep eutectic solvents as an alternative solvent in extraction techniques for monitoring pesticide and pharmaceutical residues in food and environmental matrices. She is a member of Royal Society Chemistry (MRSC) and Malaysian Institute of Chemistry (MMIC). Recently, she has been consulting the safety data sheet and involving as an internal auditor for ISO/IEC 17025: 2017.  


PENSYARAH UNIVERSITI DS51 Ph.D in Pharmaceutical Science (Goteborgs), MMed Sc. (Malaya), BSc. Forensic Science (USM)
Expertise : Bioanalysis, Pharmacokinetics and Toxicology

After earning his doctorate from Goteborg University in Sweden in 2017, Mohd Yusmaidie Aziz started his academic career as a senior lecturer at Universiti Sains Malaysia. Over the past five years, he has lectured on topics in analytical chemistry, toxicology, and exercise pharmacology to students at both the postgraduate and undergraduate levels. In his current projects, he focuses on implementing chromatographic technique, particularly mass spectrometry quantification, into the analysis of complex biological and environmental matrices. Currently, he is investigating endocrine-disrupting chemicals such as perfluoroalkyl and polyfluoroalkyl substances (PFAS) in human and environmental samples. He is also engaged in a number of research projects pertaining to liver cancer and dementia at the university level. In addition to his academic work, he has collaborated with the pharmaceutical industry on several bioequivalence studies comparing generic and innovator of various drugs. In addition to his other roles, he is the study director for an OECD GLP preclinical study at the institution. He was chosen to serve on the National Pharmaceutical Regulatory Agency (NPRA) panel of experts for the first human clinical trial at the national level. To date, over twenty-five of his scientific articles have appeared in peer-reviewed international and local journals.


UNIVERSITY LECTURER PhD in Environmental Health, MSc in Health Toxicology, B. App. Sc. Analytical Chemistry, Executive Diploma in Occupational Safety and Health
Expertise : Exposure Science

Dr. Maisarah Nasution Waras is a senior lecturer and an early career researcher in Advanced Medical and Dental Institute, Universiti Sains Malaysia. She obtained a PhD in Environmental Health from Flinders University, South Australia where she learnt about the level of pesticide (chlorpyrifos) exposure among an urban population in South Australia. She has experience in developing and validation GCMS analytical method in analyzing pesticide metabolites in urine sample. Her current research interest is chemicals exposure assessment among the occupational and non-occupational population. She also is currently teaching Analytical Chemistry course for undergraduates in USM. Prior to working in academia, she has 3 years experiences as an environmental health and safety practitioner with specific interest in industrial/occupational hygiene.